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・ Tissot (disambiguation)
・ Tissot Arena
・ Tissot's indicatrix
・ Tissotia
・ Tissotiidae
・ Tissue
・ Tissue (biology)
・ Tissue Antigens
・ Tissue bank
・ Tissue culture
・ Tissue Doppler echocardiography
・ Tissue engineering
・ Tissue Engineering and Regenerative Medicine International Society
・ Tissue expansion
・ Tissue factor
Tissue factor pathway inhibitor
・ Tissue gas
・ Tissue hydration
・ Tissue inhibitor of metalloproteinase
・ Tissue microarray
・ Tissue paper
・ Tissue plasminogen activator
・ Tissue residue
・ Tissue stress
・ Tissue transglutaminase
・ Tissue tropism
・ Tissue typing
・ Tissue-pack marketing
・ Tissue-to-air ratio
・ Tissuemed


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Tissue factor pathway inhibitor : ウィキペディア英語版
Tissue factor pathway inhibitor

Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex.
TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.
==Genetics==
The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. The gene has not been completely sequenced yet. A similar gene, termed ''TFPI2'', has been identified on chromosome 7q22; in addition to TFPI activity, its product also has retinal pigment epithelial cell growth-promoting properties.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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